Cheeseburger meatloaf Recipe is a delightful mash-up of two beloved comfort foods: the juicy flavors of a cheeseburger and the hearty satisfaction of traditional meatloaf. Whether you’re preparing it for a family dinner or a potluck gathering, this dish promises to please everyone at the table. In this blog, we’ll explore everything about cheeseburger meatloaf, from its origins to step-by-step preparation, along with tips for serving and additional insights. Let’s dive in!

What is Cheeseburger Meatloaf Recipe?
Cheeseburger meatloaf is a fusion recipe that takes the ingredients and flavors of a classic cheeseburger—ground beef, cheese, breadcrumbs, ketchup, and mustard—and transforms them into a baked meatloaf. The result is a moist, flavorful dish with a gooey cheese center and a glaze that mimics the taste of a cheeseburger.
The Origin of Cheeseburger Meatloaf Recipe
Meatloaf has a long history, dating back to ancient times when people mixed ground meat with bread or grains for economical and flavorful meals. Cheeseburger meatloaf is a more modern invention, born out of America’s love for cheeseburgers. This creative twist likely emerged in the mid-20th century when home cooks started experimenting with ways to incorporate fast-food flavors into homemade dishes.
Ingredients for Cheeseburger Meatloaf Recipe
To make the perfect cheeseburger meatloaf, you’ll need the following ingredients:
For the Meatloaf:
- 2 pounds of ground beef (preferably 80% lean)
- 1 cup of breadcrumbs
- 2 large eggs
- 1 small onion, finely chopped
- 1 cup of shredded cheddar cheese
- ½ cup of milk
- 1 tablespoon of Dijon mustard
- 2 tablespoons of ketchup
- 1 teaspoon of garlic powder
- Salt and pepper to taste
For the Glaze:
- ¼ cup of ketchup
- 2 tablespoons of mustard
- 1 tablespoon of brown sugar
Essential Equipment
Before starting, gather these tools for a seamless cooking experience:
- A large mixing bowl
- A loaf pan (9×5 inches recommended)
- A baking sheet (to catch drips)
- Measuring cups and spoons
- A spatula or wooden spoon
- Aluminum foil (optional, for covering)
Step-by-Step Preparation of Cheeseburger Meatloaf Recipe
Step 1: Preheat and Prep
- Preheat your oven to 375°F (190°C).
- Lightly grease your loaf pan to prevent sticking.
Step 2: Mix the Ingredients
- In a large mixing bowl, combine the ground beef, breadcrumbs, eggs, chopped onion, milk, Dijon mustard, ketchup, garlic powder, salt, and pepper.
- Mix gently with your hands or a spatula until the ingredients are just combined. Avoid overmixing to keep the meatloaf tender.
Step 3: Add the Cheese Center
- Spread half of the meat mixture into the loaf pan, pressing it evenly.
- Sprinkle the shredded cheddar cheese over the center, leaving a small border around the edges.
- Add the remaining meat mixture on top, carefully sealing the cheese inside.
Step 4: Prepare the Glaze
- In a small bowl, mix ketchup, mustard, and brown sugar until smooth.
- Spread this glaze evenly over the top of the meatloaf.
Step 5: Bake
- Place the loaf pan on a baking sheet to catch any drips.
- Bake in the preheated oven for 50-60 minutes, or until the internal temperature reaches 160°F (71°C).
Step 6: Rest and Serve
- Allow the meatloaf to rest for 10 minutes after removing it from the oven. This helps retain juices and makes slicing easier.
- Slice and serve warm.
Health Benefits of Cheeseburger Meatloaf Recipe

While cheeseburger meatloaf is undoubtedly a comfort food, it also offers nutritional benefits:
- Protein-packed: With ground beef and eggs as primary ingredients, this dish provides a significant protein boost.
- Rich in calcium: Thanks to the cheese and milk, it contributes to your daily calcium intake.
- Customizable: You can make healthier versions by using leaner meat, whole-grain breadcrumbs, or low-fat cheese.
Additional Information
Tips for Success:
- Don’t overmix the meat: This can result in a dense and tough texture.
- Cheese variations: Experiment with other cheeses like mozzarella, Swiss, or pepper jack for different flavor profiles.
- Add veggies: Finely diced bell peppers or grated carrots can add flavor and nutrients.
Storage Instructions:
- Refrigerate: Store leftovers in an airtight container for up to 3 days.
- Freeze: Wrap individual slices in plastic wrap and store them in a freezer-safe bag for up to 2 months.
Best Way to Serve Cheeseburger Meatloaf Recipe
- Mashed potatoes or roasted vegetables
- A crisp green salad
- Classic burger sides like fries or onion rings
- A dollop of extra ketchup or mustard for dipping
Nutritional Information
| Nutrient | Amount (per serving) |
| Calories | ~400 |
| Protein | 28g |
| Total Fat | 25g |
| Carbohydrates | 12g |
| Calcium | 15% of daily value |
Note: Nutritional values may vary based on portion size and specific ingredients.
Prep Time and Cook Time
- Preparation Time: 15 minutes
- Cook Time: 50-60 minutes
- Total Time: Approximately 1 hour 15 minutes
Conclusion
Cheeseburger meatloaf Recipe is a fun, delicious twist on traditional comfort food. It brings the nostalgic flavors of a cheeseburger to your dinner table in a hearty, satisfying form. Easy to prepare and customize, it’s a crowd-pleaser that’s perfect for weeknights or special occasions. Try this recipe today and let the cheesy goodness win over your taste buds!
FAQs
1. Can I use ground turkey instead of beef?
Absolutely! Ground turkey is a great substitute for a leaner, lighter version.
2. What’s the best way to reheat cheeseburger meatloaf Recipe?
Reheat in the oven at 350°F for about 10-15 minutes, or microwave slices for 1-2 minutes.
3. Can I make cheeseburger meatloaf gluten-free?
Yes, use gluten-free breadcrumbs or crushed gluten-free crackers.
4. What other cheeses work well in this recipe?
Swiss, mozzarella, or even smoked Gouda can add unique flavors.
5. How can I prevent my meatloaf from falling apart?
Ensure the mixture is properly bound with enough eggs and breadcrumbs, and let the meatloaf rest before slicing.